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The clotted mass is called as THROMBUS. - Predictors of Acute, Subacute and Late Stent Thrombosis After Acute MI Primary Angioplasty in the Horizons AMI Trial George D. Dangas, Alexandra J. Lansky, Early and late coronary stent thrombosis of sirolimus-eluting and paclitaxel-eluting stents in routine clinical practice: data from a large two-institutional cohort study. - SHOCK , PATHOPHYSIOLOGY Prof.M.H.MUMTAZ. R. G. Mason, Jr. One of the leading causes of morbidity and mortality in developed countries via MI and Stroke. Now customize the name of a clipboard to store your clips. The Response to Injury Theory. We use your LinkedIn profile and activity data to personalize ads and to show you more relevant ads. Thrombus Formation. Arterial hypertension Ph. Venous thromboembolism, ie, venous thrombosis and pulmonary embolism, represents a serious and potentially fatal complication for many sick, hospitalized patients, especially those who are bedridden for extended periods of time. If you continue browsing the site, you agree to the use of cookies on this website. A high incidence (80.3%) of thrombus formation corresponding to the site of infarction was observed. D., M D. Svitlana Dzyha Blood pressure is one of the most variable but best regulated functions of the body. THROMBUS BLOOD CLOT - Increase in tissue mass that results from the excess ... Gene on chromosome 21 carries gene for amyloid protein ... May revolve around amyloid protein ... - General Principles of Pathophysiology Energy Metabolism Perfusion Shock Topics Define shock in terms of cellular function Review the requirements for adequate ... Pathophysiology of vascular tone. In addition, the tendency of several platelet-derived factors (e.g. APIdays Paris 2019 - Innovation @ scale, APIs as Digital Factories' New Machi... No public clipboards found for this slide. Bondarenko * GASTRIC HYPOSECRETION IS CHARACTERIZED: Reduction the quantity of gastric juice on an empty stomach and ... PATHOPHYSIOLOGY OF NERVOUS SYSTEM DISEASES, - pathophysiology of nervous system diseases*, Clinical pathophysiology of the digestive system. Thrombosis. DEFINITION THROMBOSIS is the formation of a clotted mass of blood within the cardiovascular system. Presentation Summary : Thrombosis and embolism . VTE affects 1/1000 patients, costs $13.5 billion annually to treat, and claims 100,000 lives annually in the US. Our new CrystalGraphics Chart and Diagram Slides for PowerPoint is a collection of over 1000 impressively designed data-driven chart and editable diagram s guaranteed to impress any audience. Platelet Aggregation. It's FREE! 4. Venous thromboembolism (VTE), a disease that includes deep venous thrombosis (DVT) and pulmonary embolism (PE), is associated with high mortality, morbidity, and costs. Now customize the name of a clipboard to store your clips. Their most obvious function is to provide a semi-permeable barrier that regulates the exchange of fluid, nutrients, gases, and waste between the blood and tissues. - Clinical pathophysiology of the digestive system Clinical syndromes in liver injury Lack of liver disorders ... (involved in carbohydrate, fat, protein ... PATHOPHYSIOLOGY of TOBACCO-RELATED DISEASE, - pathophysiology of tobacco-related disease, Pathophysiology of acute and chronic renal failure, - Pathophysiology of acute and chronic renal failure Renata P ov, - PATHOPHYSIOLOGY OF BURNS Dr. Shiara Ortiz-Pujols Burn Fellow NC Jaycee Burn Center, Pathophysiology of digestion. Whether your application is business, how-to, education, medicine, school, church, sales, marketing, online training or just for fun, PowerShow.com is a great resource. Thrombosis And Embolism V4us 33rd PPT. Pathogenesis of early thrombus formation in experimental vein graft. See our User Agreement and Privacy Policy. Thrombosis is the formation of a solid mass (blood clot) from the … Plasmin Formation. - VASCULATURE, HEMODYNAMICS AND THEIR PATHOPHYSIOLOGY Blood Flow Blood vessels = arteries, veins Three tissue layers (inside to outside) Intima Epithelium + connective ... Predictors of Acute, Subacute and Late Stent Thrombosis After Acute MI Primary Angioplasty in the Horizons AMI Trial. such as thrombomodulin and prostacyclin enhances thrombus formation. 19 2. Release of tPA. Patients with cirrhosis have a hyperdynamic circulation. Boasting an impressive range of designs, they will support your presentations with inspiring background photos or videos that support your themes, set the right mood, enhance your credibility and inspire your audiences. Venous thromboembolism, ie, venous thrombosis and pulmonary embolism, represents a serious and poten­ tially fatal complication for many sick, hospitalized patients, especially those who are bedridden for extended periods of time. Eberhard F. Mammen, M.D. The dominant influence, and the one factor that by itself can lead to thrombosis, is endothelial injury.2,5,6 Endothelial Injury: Endothelial injury causes subendothelial collagen exposure and platelet adherence, among other changes; many factors can contribute to the injury, including hypertension, vasculitis, scarred valves, bacterial endotoxins, cholesterolemia, and chemicals … Pathogenesis ofThrombosis: Platelet Contribution Several different platelet agglutinating agents may share a pathway in producing white thrombi. See our Privacy Policy and User Agreement for details. Presentation Summary : exposure of the pro-thrombogenic basement membrane just below the endothelial cells thrombosis the formed thrombus will further block the lumen of the blood Fibrinolysis. THROMBOSIS. "National Research Council. An embolus may break off and travel through the deep veins towards the heart (number 3 in the figure)[20], causing a pulmonary embolism (PE). Do you have PowerPoint slides to share? Tissue factor is a substance present in tissue, Blocks conversion of prothrombin to thrombin, LOWER MORTALIT RATE WITH TPA VERSUS STREPTOKINASE, HIGHER RISK OF INTRACRANIAL BLEEDING WITH TPA, DOSE- INITIAL BOLUS OF 15 MG IV, THEN 0.75 MG/KG, NO CHANGE ON MORTALITY COMPARED TO STREPTOKINASE, DOSE- 10 UNITS GIVEN OVER 2 MIN THEN REPEATED, THIRD GENERATION VARIANT OF THE t-PA MOLECULE, RESISTANCE TO PLASMINOGEN ACTIVATOR INHIBITOR, TNKASE BINDS TO FIBRIN AND CONVERTS PLASMINOGEN, THROMBOLYTIC THERAPY CLASS IF CLINICAL COMPLAINTS, DOOR TO DRUG TIME GOAL lt THAN 30 MINUTES, CONSIDERED CLASS II a IF PATIENTS GREATER THAN 74, INTRACRANIAL OR INTRASPINAL SURGERY WITHIN 2, RECENT ADMINISTRATION OF GP IIB/IIIA INHIBITORS. Result of Thrombus? Thrombus formation in the left atrium and left ventricle is primarily due to stasis of blood which causes activation of the coagulation system. 1. Thrombus formation on disrupted atherosclerotic plaques or arterial erosions frequently causes acute coronary syndromes. Thrombosis. Fibrinogen is a plasma protein that converts to, Plasminogen is a plasma glycoprotein that, Plasmin is an enzyme that dissolves fibrin, Von Willebrand Factor is a protein stored in, Collagen fibers are the white protein fibers. × Phase 4 Thrombus Formation; 12 (No Transcript) 13 1. Neutralising antibodies are potential correlates of protection, … When inferior vena cava of rabbit was replaced by 3 cm long woven Tetron® (polyethylene terephthalates) graft under bolus injection of heparin (50 U/k… A venous thrombus has essentially two components, an inner platelet rich white thrombus forming the so-called lines of Zahn surrounded by an outer red cell dense fibrin clot . Suggested Citation:"THE PATHOGENESIS OF THROMBOSIS. Or use it to find and download high-quality how-to PowerPoint ppt presentations with illustrated or animated slides that will teach you how to do something new, also for free. Thrombus formation (called Virchow's triad): (1) endothelial injury, (2) stasis or turbulent blood flow (3) hypercoagulability of the blood. These methods of thrombus formation are, of course, artificial and only useful for developing experimental thrombi. Winner of the Standing Ovation Award for “Best PowerPoint Templates” from Presentations Magazine. SHOCK , PATHOPHYSIOLOGY Prof.M.H.MUMTAZ. Thrombosis is a significant problem in general medicine. Pathophysiology%20of%20acute%20and%20chronic%20renal%20failure. Pathogenesis of Thrombosis. Further understanding of the pathogenesis for SARS-CoV-2 will be vital in developing therapeutics, vaccines, and supportive care modalities in the treatment of covid-19. 3- mostly life saving. Thrombus formation appears to require both tissue factor and P-selectin (17,18). - Pathophysiology of digestion MD, Prof. Yu.I. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. • Cause serious complications to brain/lungs. 1- Involves only blood 1 Citations; 86 Downloads; Abstract. The white thrombus, composed pre-dominantly of platelets, forms at the point of initiation of most thrombi in the smallest to the largest vessels of the body. How it occurs • Two components : Aggregated platelets form platelet plug Mesh of cross-linked fibrin protein When body produce excessive clotting factors like platelets and Fibrin, it forms an embolus that moves around the b Thrombosis is the formation of a solid mass (blood clot) from the … 15 3. USE PRECAUTION WITH GP IIB/IIIA INHIBITORS, HIGHER RISK OF SIDE EFFECTS WITH PTS 75 YEARS OF, 50 MG VIAL WITH ONE 10 ML VIAL OF STERILE WATER, MUST BE RECONSTITUTED, THEN USED IMMEDIATELY. If you continue browsing the site, you agree to the use of cookies on this website. These thrombi occluded the vessel lumen, were usually found proximally in the coronary arteries, and were associated with a ruptured atheromatous plaque in 90.8 per cent of cases. ARTERIAL THROMBOSIS. Thrombin in turn converts fibrinogen to fibrin. Departments of Pathology and Medicine Division of Cardiology David Geffen School of Medicine at UCLA – A free PowerPoint PPT presentation (displayed as a Flash slide show) on PowerShow.com - id: 3f4967-MzFiM Or use it to create really cool photo slideshows - with 2D and 3D transitions, animation, and your choice of music - that you can share with your Facebook friends or Google+ circles. - Bern-Rotterdam Registry Early and late coronary stent thrombosis of sirolimus-eluting and paclitaxel-eluting stents in routine clinical practice: data from a large ... Clinical Pathophysiology Of Cardiovascular Diseases. CrystalGraphics 3D Character Slides for PowerPoint, - CrystalGraphics 3D Character Slides for PowerPoint. 3- … Clipping is a handy way to collect important slides you want to go back to later. Migration of thrombotic material into the circulation depends on the dynamic forces of the circulation. blood within the cardiovascular system. By Dr S Homathy. - Clinical Pathophysiology Of Cardiovascular Diseases Ph. You can change your ad preferences anytime. Propagation of a thrombus occurs towards the direction of the heart and involves the accumulation of additional platelets and fibrin. Narrowing of channel leads to TURBULENCE which precipitates clot formation. Authors; Authors and affiliations; David Bergqvist; Chapter. Platelet Adhesion. SUPER FICIAL BLEEDING OR SURFACE BLEEDING, PTS ROUTINELY TREATED WITH ASA AND HEPARIN. thrombus formation were classified under four headings on theoretical grounds. Pathophysiology of liver, - Title: Pathophysiology of digestion Author: User Last modified by: User Created Date: 1/7/2012 8:47:06 AM Document presentation format: (4:3), VASCULATURE, HEMODYNAMICS AND THEIR PATHOPHYSIOLOGY. useful for pathology students and health-concerned people. - Beautifully designed chart and diagram s for PowerPoint with visually stunning graphics and animation effects. 16 4. Looks like you’ve clipped this slide to already. Thrombosis is the formation of blood clots within a vessel. Definition • Formation of blood clot inside blood vessel. Proc Soc Exp Biol Med. clotting system. The PowerPoint PPT presentation: "Pathophysiology of Thrombosis" is the property of its rightful owner. BYERS SO, FRIEDMAN M. CONTRIBUTION OF ATHEROMATOUS GRUEL TO THROMBUS FORMATION. - PATHOPHYSIOLOGY OF HEPATIC FAILURE Assoc. of blood & blood clotting Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. It may occur in all venous sections of the body and in the extremities; the superficial as well as the deep venous system may be involved. 1969. DEFINITION Many of them are also animated. This results in an increase in viscosity and the formation of microthrombi, which are not washed away by fluid movement (number 1 in the figure); the thrombus that forms may then grow and propagate (number 2 in the figure) causing a DVT. and fibrin. 1964 Feb; 115:436–438. Accordingly, baboons treated with ticlopidine and heparin displayed a significant reduction in platelet deposition and microvascular occlusions in the ischemic basal ganglia. Platelet Activation. That's all free as well! After you enable Flash, refresh this page and the presentation should play. This means that it is anterograde in veins or retrograde in arteries. Phase 1 Release of tPA ; Phase 2 Plasmin Formation ; Phase 3 Fibrinolysis; 18 1. Clipping is a handy way to collect important slides you want to go back to later. • Obstructing blood flow through the circulatory system. And, best of all, most of its cool features are free and easy to use. This may promote the development of local vasospasm, which worsens coronary occlusion. Presentation Summary : Thrombosis and embolism . 2- composed of platelets - CrystalGraphics offers more PowerPoint templates than anyone else in the world, with over 4 million to choose from. doi: 10.17226/20259. Inappropriate thrombus formation is a disruption of homeostasis and may result from an alteration in any of the factors listed below. Pathogenesis of Atherosclerosis Judith Berliner, Ph.D. CRAWFORD T. Morphological aspects in the pathogenesis of atherosclerosis. 2- composed of platelets and fibrin. Cardiovascular System 182469 PPT. Thrombosis.Washington, DC: The National Academies Press. They'll give your presentations a professional, memorable appearance - the kind of sophisticated look that today's audiences expect. Current antithrombotic therapies available as long-term treatment for patients with cardiovascular disease are often not effective … The endothelial cells that line blood vessels provide an active, dynamic interface between the blood stream and the arterial wall. TXA 2, 5-HT) to cause vasoconstriction is increased in the absence of endothelial-derived relaxing factors. If so, share your PPT presentation slides online with PowerShow.com.  THROMBOSIS is the formation of a clotted mass of 1- Involves only blood clotting system. precipitating clot formation . - Pathophysiology of vascular tone. 1991 Dec;16(6):395-404. Thrombosis, Ulceration, and Stroke Pathogenesis Mark Fisher, MD; Annlia Paganini-Hill, PhD; Aldana Martin, HT, HTL; Michele Cosgrove, MD; James F. Toole, MD; Henry J.M. 20 3. can lead to: stroke, heart attack, organ failures Chest pain and shortness of breath Pain, redness, warmth, and swelling in the lower leg Headaches, speech changes, paralysis (an inability to move), dizziness, and trouble speaking and understanding Heart Itoh T(1), Kambayashi J, Tsujinaka T, Sakon M, Ohshiro T, Mori T. Author information: (1)Second Department of Surgery, Osaka University Medical School. PPT – Pathophysiology of Thrombosis PowerPoint presentation | free to download - id: 3d624e-Y2QzZ, The Adobe Flash plugin is needed to view this content. Macrocytic-Normochromic (Megaloblastic) Most common type ... - ... Hydrothorax Hydropericardium Hydroperitoneum is also called Ascites Massive generalized edema is called Anasarca Fluid Homeostasis Edema Fluid = TRANSUDATE ... Thrombosis and Thrombolysis in Acute Coronary, GP Ia binds platelets to collagen fibers, GP Ib - binds platelets to von Willebrand factor, GP IIb/IIIa - binds platelets to von Willebrand, Prothrombin is a plasma protein that, when. But even nonhospitalized, ambulant patients and apparently healthy individuals may encounter this problem.  The clotted mass is called as THROMBUS. Pathogenesis of Atherosclerosis. THROMBUS BLOOD CLOT 1- Involves wall of blood vessels, formed elements of blood & blood clotting system. system. You just clipped your first slide! 2- composed of fibrin only. 17 Phases of Thrombolysis. Thrombus formation can have one of four outcomes: propagation, embolization, dissolution, and organization and recanalization. D., M D. Nataliya Potikha Regulation of arterial pressure ( P) CO leads to PR and P ... - Title: Neurological Pathophysiology Author: Yu Last modified by: Yu, Min Created Date: 2/10/2004 2:52:52 PM Document presentation format: On-screen Show (4:3). vessels, formed elements J Atheroscler Res. Or use it to upload your own PowerPoint slides so you can share them with your teachers, class, students, bosses, employees, customers, potential investors or the world. Food and agriculture organization (FAO) & veterinary sector in India, Ultrastructure of cells of respiratory system, Customer Code: Creating a Company Customers Love, Be A Great Product Leader (Amplify, Oct 2019), Trillion Dollar Coach Book (Bill Campbell). 3- may be life-threatening. 2- composed of fibrin only. Details on atheroscleroris-thrombosis relationship Slides 30-32. Atrial fibrillation is the commonest underlying card … Etiology and pathogenesis of thromboembolism Herz. Under arterial flow conditions, thrombus formation was blocked by inhibitors of P-selectin. Thrombus formation on disrupted atherosclerotic plaques or arterial erosions frequently causes acute coronary syndromes. - DEEP VENOUS THROMBOSIS DR.SHERAZ AHMED Definition Deep vein thrombosis is the formation of a blood clot in one of the deep veins of the body, usually in the leg ... | PowerPoint PPT presentation | free to view. presentations for free. Thrombosis And Embolism V4us 33rd PPT. 23 Tissue factor and P-selectin appear to both be necessary for thrombus formation and they appear to both be resident on microparticles derived from monocytes, as indicated by the presence of monocyte proteins on the microparticles. They are all artistically enhanced with visually stunning color, shadow and lighting effects. Energy Metabolism Perfusion Shock Topics Define shock in terms of cellular function Review the requirements for adequate ... - Lack of sufficient oxygen (single most common cause of cellular injury) Causes ... Pernicious Anemia. 14 2. And they’re ready for you to use in your PowerPoint presentations the moment you need them. Prof. J. Plevkova MD, PhD. To view this presentation, you'll need to allow Flash. More data are needed to understand the determinants of healthy versus dysfunctional response and immune markers for protection and the severity of disease. 1961 Jan-Feb; 1:3–25. By Dr S Homathy. PowerShow.com is a leading presentation/slideshow sharing website. Thrombosis, the formation of a blood clot (thrombus) that tends to plug functionally normal blood vessels, is one of the major causes of death in Western societies. Severe atherosclerosis of the aorta has been identified as an important morphologic indicator of an increased risk for thromboembolism. The first was changes in the coagulability of the blood, the second changes in the formed elements of the blood, the third changes in the circulatory blood flow andthelast changesin thevessel walls. 1- Involves wall of blood Arterial hypertension. Their relationship to naturally occurring thrombus formation in humans is unknown, but they do offer a model for studying thrombi that are spatially and temporally defined. 3- may be life-threatening. a haemodynamic disorder which has serious consequences. It can result in long-term complications that include postthrombotic syndrome (PTS) adding to its morbidity.

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